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Ecocardiografía 5 minutos antes de empezar  







Redactor


Derliz Mereles procede de Asunción, Paraguay, y es miembro del Departamento de Cardiología del Hospital de la Universidad de Heidelberg desde 1993, así como Jefe del Laboratorio de Ecocardiografía desde 2009.

Sus estudios de medicina los culminó él en Paraguay. Obtuvo el título de "Doctor en Medicina y Cirugía" de la Universidad Nacional de Asunción en 1987, y el título de "Doctoris medicinae" de la Universidad Ruperto Carola de Heidelberg en el 2004. En 1999 obtuvo el título de especialista en cardiología, otorgado por el Círculo Paraguayo de Médicos.

Su larga experiencia en el campo de la ecocardiografía lo quiere transmitir a través de esta instrucción elemental.





Trabajos científicos y publicaciones

echoforum
PubMed
Google Scholar

ORCID



2020

Gi WT, Sedaghat-Hamedani F, Shirvani Samani O, Kayvanpour E, Herpel E, Arif R, Riffel J, Mereles D, Katus HA, Meder B.
Cardiac Myxoma in a Patient With Hypertrophic Cardiomyopathy.
JACC: Case Reports 2020. doi.org/10.1016/j.jaccas.2019.11.072
open source


Geis N, Raake P, Kiriakou C, Mereles D, Frankenstein L, Abu-Sharar H, Chorianopoulos E, Katus HA, Bekeredjian R,
Pleger ST.
Temporary oral anticoagulation after MitraClip - a strategy to lower the incidence of post-procedural stroke?
Acta Cardiol. 2020;75:61-67.
PubMed




2019

Giannitsis E, Mueller-Hennessen M, Zeller T, Schuebler A, Aurich M, Biener M, Vafaie M, Stoyanov KM, Ochs M, Riffel J, Mereles D, Blankenberg S, Katus HA.
Gender-specific reference values for high-sensitivity cardiac troponin T and I in well-phenotyped healthy individuals and validity of high-sensitivity assay designation.
Clin Biochem. 2019. pii: S0009-9120(19)30918-X.
open source


Gomes B, Hees K, Hund H, Mereles D, Meder B, Katus HA, Bekeredjian R.
Prevalence and relevance of impaired left ventricular function in chronic moderate regurgitation of native aortic valves.
Acta Cardiol. 2019;16:1-8.
PubMed


Greiner S, André F, Heimisch M, Aurich M, Steen H, Katus HA, Mereles D.
A closer look at right ventricular 3D volume quantification by transthoracic echocardiography and cardiac MRI.
Clin Radiol. 2019;74:490.e7-490.e14.
PubMed




Aurich M, Niemers M, Fuchs P, Greiner S, Müller-Hennessen M, Uhlmann L, Giannitsis E, Ehlermann P, Meder B, Katus HA, Mereles D.
Pathophysiological background and prognostic implication of systolic aortic root motion in non-ischemic dilated cardiomyopathy.
Sci Rep. 2019;9:3866. doi: 10.1038/s41598-019-40386-z.
open source




Hirschberg K, Reinhart M, Mereles D, Uhlmann L, André F, Riffel J, Ochs M, Katus HA.
Echocardiographic calcification score in patients with low/intermediate cardiovascular risk.
Clin Res Cardiol. 2019;108:194-202.
PubMed




2018

Greiner S, Goppelt F, Aurich M, Katus HA, Mereles D.
Prognostic relevance of the right ventricular myo-mechanical index (RV-MMI) in patients with precapillary pulmonary hypertension.
Open Heart. 2018;5:e000903.
open source


Kovacs G, Dumitrescu D, Barner A, Greiner S, Grünig E, Hager A, Köhler T, Kozlik-Feldmann R, Kruck I, Lammers AE, Mereles D, Meyer A, Meyer J, Pabst S, Seyfarth HJ, Sinning C, Sorichter S, Stähler G, Wilkens H, Held M.
Definition, clinical classification and initial diagnosis of pulmonary hypertension: Updated recommendations from the Cologne Consensus Conference 2018.
Int J Cardiol. 2018;272S:11-19.
open source


Maurer MS, Schwartz JH, Gundapaneni B, Elliott PM, Merlini G, Waddington-Cruz M, Kristen AV, Grogan M, Witteles R, Damy T, Drachman BM, Shah SJ, Hanna M, Judge DP, Barsdorf AI, Huber P, Patterson TA, Riley S, Schumacher J, Stewart M, Sultan MB, Rapezzi C; ATTR-ACT Study Investigators.
Tafamidis Treatment for Patients with Transthyretin Amyloid Cardiomyopathy.
N Engl J Med. 2018;379:1007-1016.
open source


Korff S, Enders-Gier P, Uhlmann L, Aurich M, Greiner S, Hirschberg K, Katus HA, Mereles D.
Systolic pulmonary artery pressure assessed during routine exercise Doppler echocardiography: insights of a real-world setting in patients with elevated pulmonary pressures.
Int J Cardiovasc Imaging. 2018;34:1215-1225.
PubMed


Chaves G, Britez N, Oviedo G, Gonzalez G, Italiano C, Blanes M, Sandoval G, Mereles D.
Heavy drinkers of Ilex paraguariensis beverages show lower lipid profiles but higher body weight.
Phytother Res. 2018;32:1030-1038.
PubMed


Aurich M, Fuchs P, Müller-Hennessen M, Uhlmann L, Niemers M, Greiner S, Täger T, Hirschberg K, Ehlermann P, Meder B, Frankenstein L, Giannitsis E, Katus HA, Mereles D.
Unidimensional Longitudinal Strain: A Simple Approach for the Assessment of Longitudinal Myocardial Deformation by Echocardiography.
J Am Soc Echocardiogr. 2018;31:733-742.
PubMed


Greiner S, Jud A, Aurich M, Geisenberger C, Uhlmann L, Hilbel T, Kieser M, Katus HA, Mereles D.
Prognostic relevance of elevated pulmonary arterial pressure assessed non-invasively: Analysis in a large patient cohort with invasive measurements in near temporal proximity.
PLoS One. 2018;13:e0191206.
open source


Haas J, Mester S, Lai A, Frese KS, Sedaghat-Hamedani F, Kayvanpour E, Rausch T, Nietsch R, Boeckel JN, Carstensen A, Völkers M, Dietrich C, Pils D, Amr A, Holzer DB, Martins Bordalo D, Oehler D, Weis T, Mereles D, Buss S, Riechert E, Wirsz E, Wuerstle M, Korbel JO, Keller A, Katus HA, Posch AE, Meder B.
Genomic structural variations lead to dysregulation of important coding and non-coding RNA species in dilated cardiomyopathy.
EMBO Mol Med. 2018;10:107-120.
open source


Siepen FAD, Bauer R, Voss A, Hein S, Aurich M, Riffel J, Mereles D, Röcken C, Buss SJ, Katus HA, Kristen AV.
Predictors of survival stratification in patients with wild-type cardiac amyloidosis.
Clin Res Cardiol. 2018;107:158-169.
PubMed


Geis N, Raake P, Lewening M, Mereles D, Chorianopoulos E, Frankenstein L, Katus HA, Bekeredjian R, Pleger ST.
Percutaneous repair of mitral valve regurgitation in patients with severe heart failure: comparison with optimal medical treatment.
Acta Cardiol. 2018;73:378-386.
PubMed


Geis N, Raake P, Mereles D, Chorianopoulos E, Szabo G, Katus HA, Bekeredjian R, Pleger ST.
Percutaneous repair of severe mitral valve regurgitation secondary to chordae rupture in octogenarians using MitraClip.
J Interv Cardiol. 2018;31:76-82.
open source


Siepen FAD, Bauer R, Voss A, Hein S, Aurich M, Riffel J, Mereles D, Röcken C, Buss SJ, Katus HA, Kristen AV.
Predictors of survival stratification in patients with wild-type cardiac amyloidosis.
Clin Res Cardiol. 2018;107:158-169.
PubMed




2017

Ochs MM, Fritz T, Arenja N, Riffel J, Andre F, Mereles D, Siepen FAD, Hegenbart U, Schönland S, Katus HA, Friedrich MGW, Buss SJ.
Regional differences in prognostic value of cardiac valve plane displacement in systemic light-chain amyloidosis.
J Cardiovasc Magn Reson. 2017;19:87. doi: 10.1186/s12968-017-0402-2.
open source


Giusca S, Mereles D, Ochs A, Buss S, André F, Seitz S, Riffel J, Fortner P, Andrulis M, Schönland S, Katus HA,
Korosoglou G.
Incremental value of cardiac magnetic resonance for the evaluation of cardiac tumors in adults: experience of a high volume tertiary cardiology centre.
Int J Cardiovasc Imaging. 2017;33:879-888.
PubMed


Ochs MM, Fritz T, André F, Riffel J, Mereles D, Müller-Hennessen M, Giannitsis E, Katus HA, Friedrich MG, Buss SJ.
A comprehensive analysis of cardiac valve plane displacement in healthy adults: age-stratified normal values by cardiac magnetic resonance.
Int J Cardiovasc Imaging. 2017;33:721-729.
PubMed




2016

Ochs MM, Riffel J, Kristen AV, Hegenbart U, Schönland S, Hardt SE, Katus HA, Mereles D, Buss SJ.
Anterior Aortic Plane Systolic Excursion: A Novel Indicator of Transplant-Free Survival in Systemic Light-Chain Amyloidosis.
J Am Soc Echocardiogr. 2016;29:1188-1196.
PubMed


Kovacs G, Dumitrescu D, Barner A, Greiner S, Grünig E, Hager A, Köhler T, Kozlik-Feldmann R, Kruck I, Lammers A, Mereles D, Meyer A, Meyer FJ, Pabst S, Seyfarth HJ, Sinning C, Sorichter S, Stähler G, Wilkens H, Held M. [Clinical classification and initial diagnosis of pulmonary hypertension: recommendations of the Cologne Consensus Conference 2016].
Dtsch Med Wochenschr. 2016;141(S01):S10-S18.
PubMed


Kallenberger SM, Schmid C, Wiedmann F, Mereles D, Katus HA, Thomas D, Schmidt C. A Simple, Non-Invasive Score to Predict Paroxysmal Atrial Fibrillation.
PLoS One. 2016;11:e0163621.
open source


Amr A, Kayvanpour E, Sedaghat-Hamedani F, Passerini T, Mihalef V, Lai A, Neumann D, Georgescu B, Buss S, Mereles D, Zitron E, Posch AE, Würstle M, Mansi T, Katus HA, Meder B. Personalized Computer Simulation of Diastolic Function in Heart Failure.
Genomics Proteomics Bioinformatics. 2016;14:244-52.
open source


Vermeer AM, Lodder EM, Thomas D, Duijkers FA, Marcelis C, van Gorselen EO, Fortner P, Buss SJ, Mereles D, Katus HA, Wilde AA, Bezzina CR, Boekholdt SM, Schweizer PA, Christiaans I. Dilation of the Aorta Ascendens Forms Part of the Clinical Spectrum of HCN4 Mutations.
J Am Coll Cardiol. 2016;67:2313-5.
open source


Mereles D, Aurich M, Greiner S, Riffel J, Buss SJ, Kristen AV, Katus HA.
Diagnosis of cardiac involvement in systemic amyloidosis by state-of-the-art echocardiography: where are we now?.
Expert Opin on Orphan Drugs. 2016, DOI:10.1080/21678707.2016.1179573.
online




Aurich M, Keller M, Greiner S, Steen H, Aus dem Siepen F, Riffel J, Katus HA, Buss SJ, Mereles D.
Left ventricular mechanics assessed by two-dimensional echocardiography and cardiac magnetic resonance imaging: comparison of high-resolution speckle tracking and feature tracking.
Eur Heart J Cardiovasc Imaging. 2016 Mar 24. pii: jew042. [Epub ahead of print]
PubMed




2015

Chaves G, Brítez N, Maciel V, Klinkhof A, Mereles D.
[Prevalence of cardiovascular risk factors in an urban ambulatory adult population: AsuRiesgo study, Paraguay].
Rev Panam Salud Publica. 2015;38:136-43.
open source


Sedaghat-Hamedani F, Kayvanpour E, Frankenstein L, Mereles D, Amr A, Buss S, Keller A, Giannitsis E, Jensen K, Katus HA, Meder B.
Biomarker Changes after Strenuous Exercise Can Mimic Pulmonary Embolism and Cardiac Injury-A Metaanalysis of 45 Studies.
Clin Chem. 2015;61:1246-55.
PubMed


Kayvanpour E, Mansi T, Sedaghat-Hamedani F, Amr A, Neumann D, Georgescu B, Seegerer P, Kamen A, Haas J, Frese KS, Irawati M, Wirsz E, King V, Buss S, Mereles D, Zitron E, Keller A, Katus HA, Comaniciu D, Meder B.
Towards Personalized Cardiology: Multi-Scale Modeling of the Failing Heart.
PLoS One.2015;10:e0134869.
open source


Rivinius R, Helmschrott M, Koch V, Sedaghat-Hamedani F, Fortner P, Darche FF, Thomas D, Ruhparwar A, Schmack B, Karck M, Akhavanpoor M, Erbel C, Gleissner CA, Buss SJ, Mereles D, Ehlermann P, Katus HA, Doesch AO.
Constrictive Pericarditis in the Presence of Remaining Remnants of a Left Ventricular Assist Device in a Heart Transplanted Patient.
Case Rep Transplant. 2015;2015:372698.
open source


Hirschberg K, Reinhart M, Konstandin M, Uhlmann L, Katus HA, Mereles D.
Diagnostic and prognostic value of a novel cardiac calcification score for coronary artery disease by transthoracic echocardiography.
Int J Cardiol. 2015;190:332-4.
PubMed


Dehnert C, Mereles D, Greiner S, Albers D, Scheurlen F, Zügel S, Böhm T, Vock P, Maggiorini M, Grünig E, Bärtsch P.
Exaggerated hypoxic pulmonary vasoconstriction without susceptibility to high altitude pulmonary edema.
High Alt Med Biol. 2015;16:11-7.
PubMed


Chaves G, Britez N, Munzinger J, Uhlmann L, Gonzalez G, Oviedo G, Chaparro V, Achon O, Bruckner T, Kieser M, Katus HA, Mereles D.
Education to a Healthy Lifestyle Improves Symptoms and Cardiovascular Risk Factors - AsuRiesgo Study.
Arq Bras Cardiol. 2015;104:347-55.
open source


Bekeredjian R, Bodingbauer D, Hofmann NP, Greiner S, Schuetz M, Geis NA, Kauczor HU, Bryant M, Chorianopoulos E, Pleger ST, Mereles D, Katus HA, Korosoglou G.
The extent of aortic annulus calcification is a predictor of postprocedural eccentricity and paravalvular regurgitation: a pre- and postinterventional cardiac computed tomography angiography study.
J Invasive Cardiol. 2015;27:172-80.
PubMed


Riffel JH, Keller MG, Aurich M, Sander Y, Andre F, Giusca S, Aus dem Siepen F, Seitz S, Galuschky C, Korosoglou G, Mereles D, Katus HA, Buss SJ.
Assessment of global longitudinal strain using standardized myocardial deformation imaging: a modality independent software approach.
Clin Res Cardiol. 2015;104:591-602.
PubMed


Zylla MM, Pohlmeier M, Hess A, Mereles D, Kieser M, Bruckner T, Scholz E, Zitron E, Schweizer PA, Katus HA, Thomas D.
Prevalence of intracardiac thrombi under phenprocoumon, direct oral anticoagulants (dabigatran and rivaroxaban), and bridging therapy in patients with atrial fibrillation and flutter.
Am J Cardiol. 2015;115:635-40.
PubMed


Riffel JH, Mereles D, Emami M, Korosoglou G, Kristen AV, Aurich M, Voss A, Schonland SO, Hegenbart U, Hardt SE, Katus HA, Buss SJ.
Prognostic significance of semiautomatic quantification of left ventricular long axis shortening in systemic light-chain amyloidosis.
Amyloid. 2015;22:45-53.
PubMed


Li J, Franke J, Pribe-Wolferts R, Meder B, Ehlermann P, Mereles D, Andre F, Abdelrazek MA, Merten C, Schweizer PA, Becker R, Katus HA, Thomas D.
Effects of ß-blocker therapy on electrocardiographic and echocardiographic characteristics of left ventricular noncompaction.
Clin Res Cardiol. 2015;104:241-9.
PubMed


Haas J, Frese KS, Peil B, Kloos W, Keller A, Nietsch R, Feng Z, Müller S, Kayvanpour E, Vogel B, Sedaghat-Hamedani F, Lim WK, Zhao X, Fradkin D, Köhler D, Fischer S, Franke J, Marquart S, Barb I, Li DT, Amr A, Ehlermann P, Mereles D, Weis T, Hassel S, Kremer A, King V, Wirsz E, Isnard R, Komajda M, Serio A, Grasso M, Syrris P, Wicks E, Plagnol V, Lopes L, Gadgaard T, Eiskjær H, Jørgensen M, Garcia-Giustiniani D, Ortiz-Genga M, Crespo-Leiro MG, Deprez RH, Christiaans I, van Rijsingen IA, Wilde AA, Waldenstrom A, Bolognesi M, Bellazzi R, Mörner S, Bermejo JL, Monserrat L, Villard E, Mogensen J, Pinto YM, Charron P, Elliott P, Arbustini E, Katus HA, Meder B.
Atlas of the clinical genetics of human dilated cardiomyopathy.
Eur Heart J. 2015;36:1123-35a.
PubMed




2014

Kovacs G, Pienn M, Grünig E, Mereles D, Claussen M, Dandel M, Dumitrescu D, Kruck I, Bruch L, Blindt R, Holt S, Sinn L, Sorichter S, Winkler J, Olschewski H.
[Modern imaging methods in the management of pulmonary hypertension].
Dtsch Med Wochenschr. 2014;139 Suppl 4:S121-5.
PubMed


Greiner S, Jud A, Aurich M, Hess A, Hilbel T, Hardt S, Katus HA, Mereles D.
Reliability of noninvasive assessment of systolic pulmonary artery pressure by Doppler echocardiography compared to right deart catheterization: analysis in a large patient population.
J Am Heart Assoc. 2014;3:e001103 doi: 10.1161/JAHA.114.001103.
open source


Aurich M, André F, Keller M, Greiner S, Hess A, Buss SJ, Katus HA, Mereles D.
Assessment of left ventricular volumes with echocardiography and cardiac magnetic resonance imaging: real-life evaluation of standard versus new semiautomatic methods.
J Am Soc Echocardiogr. 2014 Aug 14. [Epub ahead of print]
PubMed


Schweizer PA, Schröter J, Greiner S, Haas J, Yampolsky P, Mereles D, Buss SJ, Seyler C, Bruehl C, Draguhn A, Koenen M, Meder B, Katus HA, Thomas D.
The symptom complex of familial sinus node dysfunction and myocardial noncompaction is associated with mutations in the HCN4 channel.
J Am Coll Cardiol 2014;64:757–67.
PubMed


Greiner S, Heimisch M, Aurich M, Heß JA, Katus HA, Mereles D.
Multiplane two-dimensional strain echocardiography for segmental analysis of right ventricular mechanics: New-RV study.
Clin Res Cardiol. 2014 May 16. [Epub ahead of print]
PubMed


Buss SJ, Krautz B, Schnackenburg B, Abdel-Aty H, Santos MF, Andre F, Maertens MJ, Mereles D, Korosoglou G, Giannitsis E, Katus HA, Steen H.
Classification of diastolic function with phase-contrast cardiac magnetic resonance imaging: validation with echocardiography and age-related reference values.
Clin Res Cardiol. 2014;103:441-50.
PubMed


Buss SJ, Schulz F, Mereles D, Hosch W, Galuschky C, Schummers G, Stapf D, Hofmann N, Giannitsis E, Hardt SE, Kauczor HU, Katus HA, Korosoglou G.
Quantitative analysis of left ventricular strain using cardiac computed tomography.
Eur J Radiol. 2014;83:e123-30.
PubMed


Bikiri E, Mereles D, Voss A, Greiner S, Hess A, Buss SJ, Hofmann NP, Giannitsis E, Katus HA, Korosoglou G.
Dobutamine stress cardiac magnetic resonance versus echocardiography for the assessment of outcome in patients with suspected or known coronary artery disease. Are the two imaging modalities comparable?
Int J Cardiol. 2014;171:153-60.
PubMed




2013

Pleger ST, Schulz-Schönhagen M, Geis N, Mereles D, Chorianopoulos E, Antaredja M, Lewening M, Katus HA, Bekeredjian R.
One year clinical efficacy and reverse cardiac remodelling in patients with severe mitral regurgitation and reduced ejection fraction after MitraClip© implantation.
Eur J Heart Fail. 2013 Mar 19. [Epub ahead of print]
PubMed


Haas J, Frese KS, Park YJ, Keller A, Vogel B, Lindroth AM, Weichenhan D, Franke J, Fischer S, Bauer A, Marquart S, Sedaghat-Hamedani F, Kayvanpour E, Köhler D, Wolf NM, Hassel S, Nietsch R, Wieland T, Ehlermann P, Schultz JH, Dösch A, Mereles D, Hardt S, Backs J, Hoheisel JD, Plass C, Katus HA, Meder B.
Alterations in cardiac DNA methylation in human dilated cardiomyopathy.
EMBO Mol Med. 2013;5:413-429.
PubMed


Greiner S, André F, Heimisch M, Heß A, Steen H, Katus HA, Mereles D. Non-invasive quantification of right ventricular systolic function by echocardiography: a new semi-automated approach.
Clin Res Cardiol. 2013;102:229-235.
PubMed




2012

Buss SJ, Emami M, Mereles D, Korosoglou G, Kristen AV, Voss A, Schellberg D, Zugck C, Galuschky C, Giannitsis E, Hegenbart U, Ho AD, Katus HA, Schonland SO, Hardt SE.
Longitudinal left ventricular function for prediction of survival in systemic light-chain amyloidosis: incremental value compared with clinical and biochemical markers.
J Am Coll Cardiol. 2012;60:1067-1076.
PubMed


Mansi T, Mihalef V, Sharma P, Georgescu B, Zheng X, Rapaka S, Kamen A, Mereles D, Steen H, Meder B, Katus H, Comaniciu D. Data-driven computational models of heart anatomy, mechanics and hemodynamics: An integrated framework.
Biomedical Imaging (ISBI), 2012 9th IEEE International Symposium.
open source


Kristen AV, Lehrke S, Buss S, Mereles D, Steen H, Ehlermann P, Hardt S, Giannitsis E, Schreiner R, Haberkorn U, Schnabel PA, Linke RP, Röcken C, Wanker EE, Dengler TJ, Altland K, Katus HA.
Green tea halts progression of cardiac transthyretin amyloidosis: an observational report.
Clin Res Cardiol. 2012 May 15. [Epub ahead of print]
PubMed


Buss SJ, Mereles D, Emami M, Korosoglou G, Riffel JH, Bertel D, Schonland SO, Hegenbart U, Katus HA, Hardt SE.
Rapid assessment of longitudinal systolic left ventricular function using speckle tracking of the mitral annulus.
Clin Res Cardiol. 2012;101:273-280.
PubMed


Sommer AP, Bieschke J, Friedrich RP, Zhu D, Wanker EE, Fecht HJ, Mereles D, Hunstein W.
670 nm Laser Light and EGCG Complementarily Reduce Amyloid-ß Aggregates in Human Neuroblastoma Cells: Basis for Treatment of Alzheimer's Disease?
Photomed Laser Surg. 2012;30:54-60.
PubMed




2011

Mereles D, Hunstein W.
Epigallocatechin-3-gallate (EGCG) for Clinical Trials: More Pitfalls than Promises?
Int J Mol Sci. 2011;12:5592-5603.
open source


Vogel B, Thomas D, Mereles D, Rottbauer W, Katus HA.
Systemic Embolization and Myocardial Infarction due to Clinically Unrecognized Left Atrial Myxoma.
Case Report Med. 2011;2011:159024. Epub 2011 Nov 30.
PubMed


Buss SJ, Mereles D, Emami M, Korosoglou G, Riffel JH, Bertel D, Schonland SO, Hegenbart U, Katus HA, Hardt SE.
Rapid assessment of longitudinal systolic left ventricular function using speckle tracking of the mitral annulus.
Clin Res Cardiol. 2011 Dec 4. [Epub ahead of print]
PubMed


Pleger ST, Mereles D, Schulz-Schönhagen M, Krumsdorf U, Chorianopoulos E, Rottbauer W, Katus HA, Bekeredjian R.
Acute safety and 30-day outcome after percutaneous edge-to-edge repair of mitral regurgitation in very high-risk patients.
Am J Cardiol. 2011 Sep 3. [Epub ahead of print]
PubMed


Bekeredjian R, Mereles D, Pleger S, Krumsdorf U, Katus HA, Rottbauer W.
Large atrial thrombus formation after MitraClip implantation: is anticoagulation mandatory?
J Heart Valve Dis. 2011;20:146-148.
PubMed


Buss SJ, Mereles D, Katus HA, Hardt SE.
Left ventricular non-compaction cardiomyopathy mimicking an infiltrative cardiac disease.
Int J Cardiol. 2011;147:e41-43.
PubMed


Barrio JP, Cura G, Ramallo G, Diez M, Vigliano CA, Katus HA, Mereles D.
Heart transplantation in rapidly progressive end-stage heart failure associated with celiac disease.
BMJ Case Reports 2011; doi:10.1136/bcr.12.2010.3624
PubMed




2010

Konstandin MH, Korosoglou G, Hosch W, Hardt SE, Katus HA, Mereles D.
Severe right ventricular outflow tract obstruction caused by Non-Hodgkin lymphoma: complete regression after one course of bendamustine/rituximab therapy.
J Am Soc Echocardiogr. 2010 Oct 23. [Epub ahead of print]
PubMed


Korosoglou G, Ehlermann P, Mereles D, Giannitsis E, Katus HA.
Non-compaction cardiomyopathy of the left ventricle diagnosed by cardiac magnetic resonance in a 2-generation family.
Clin Res Cardiol. 2010 Sep 7. [Epub ahead of print]
PubMed


Hess A, Rottbauer W, Katus HA, Mereles D.
Exaggerated apical trabeculations mimicking left ventricular thrombus: a 3D TEE perspective.
Clinical Research in Cardiology 2010 Jul 1. [Epub ahead of print]
PubMed


Wolf D, Benz A, Hardt SE, Katus HA, Mereles D.
Trepopnea Associated with Paroxysmal Severe Tricuspid Regurgitation Triggered at Left Lateral Decubitus Position.
Echocardiography 2010 Jun 9. [Epub ahead of print]
PubMed


Möller T, Brun H, Fredriksen PM, Holmstrøm H, Peersen K, Pettersen E, Grünig E, Mereles D, Thaulow E.
Right ventricular systolic pressure response during exercise in adolescents born with atrial or ventricular septal defect.
The American Journal of Cardiology 2010;105:1610-1616.
PubMed


Filusch A, Mereles D, Gruenig E, Buss S, Katus HA, Meyer FJ.
Strain and strain rate echocardiography for evaluation of right ventricular dysfunction in patients with idiopathic pulmonary arterial hypertension.
Clinical Research in Cardiololgy 2010 Mar 30. [Epub ahead of print]
PubMed


Mereles D, Buss SJ, Hardt SE, Hunstein W, Katus HA.
Effects of the main green tea polyphenol epigallocatechin-3-gallate on cardiac involvement in patients with AL amyloidosis.
Clinical Research in Cardiology 2010 Mar 10. [Epub ahead of print]
PubMed


Hess A, Korosoglou G, Rottbauer W, Katus HA, Mereles D.
Successful treatment of cardiac manifestation of eosinophilic leukemia.
Clinical Research in Cardiology 2010;99:409-410.
PubMed


Konstandin MH, Hardt SE, Katus HA, Mereles D.
Pronounced coronary artery calcification: Casual finding in transthoracic echocardiography.
International Journal of Cardiology 2009 Nov 5. [Epub ahead of print]
PubMed


Mayer C, Frank C, Frank D, Tochtermann U, Rehnitz C, Grenacher L, Hardt SE, Katus HA, Mereles D.
Left atrial wall dissection, mitral valve prosthesis dehiscence and pericardial hematoma: complex findings after successful cardiac resuscitation.
Clinical Research in Cardiology 2010;99:57-58.
PubMed




2009

Grünig E, Weissmann S, Ehlken N, Fijalkowska A, Fischer C, Fourme T, Galié N, Ghofrani A, Harrison RE, Huez S, Humbert M, Janssen B, Kober J, Koehler R, Machado RD, Mereles D, Naeije R, Olschewski H, Provencher S, Reichenberger F, Retailleau K, Rocchi G, Simonneau G, Torbicki A, Trembath R, Seeger W.
Stress Doppler Echocardiography in Relatives of Patients With Idiopathic and Familial Pulmonary Arterial Hypertension. Results of a Multicenter European Analysis of Pulmonary Artery Pressure Response to Exercise and Hypoxia.
Circulation 2009;119:1747-1757.
PubMed


Bär H, Siegmund A, Wolf D, Hardt S, Katus HA, Mereles D.
Prevalence of asymptomatic mitral valve malformations.
Clinical Research in Cardiology 2009;98:305-309.
PubMed


Buss SJ, Mereles D, Katus HA, Hardt SE.
Left ventricular non-compaction cardiomyopathy mimicking an infiltrative cardiac disease.
International Journal of Cardiololy 2009 Feb 19. [Epub ahead of print]
PubMed


Buss SJ, Wolf D, Mereles D, Blank N, Katus HA, Hardt SE.
A rare case of reversible constrictive pericarditis with severe pericardial thickening in a patient with adult onset Still's disease.
International Journal of Cardiology 2009 Jan 29. [Epub ahead of print]
PubMed


Bär H, Katus HA, Mereles D.
Accessory mitral valve as a potential source of cardioembolism.
International Journal of Cardiology 2009;131:e76-77. Epub 2007 Aug 20.
PubMed


Bär H, Katus HA, Mereles D.
Unexpected pulsatile intracardiac mass.
International Journal of Cardiology 2009;135:e52-54
PubMed


Bär H, Katus HA, Mereles D.
Biventricular involvement in transient apical ballooning syndrome.
International Journal of Cardiology 2009;133:e79-80.
PubMed


Buss SJ, Johanssen C, Katus HA, Mereles D.
A trapped thrombus in the right ventricle.
International Journal of Cardiology 2009;133:e60-61
PubMed




2008

Hansen A, Mereles D.
Cardiac complications in Whipple's disease.
European Journal of Echocardiography 2008;9:426-427.
PubMed


Mereles D, Wanker EE, Katus HA.
Therapy effects of green tea in a patient with systemic light-chain amyloidosis.
Clinical Research in Cardiology 2008;97:341-344.
PubMed


Kasimir MT, Mereles D, Aigner C, Jaksch P, Benz A, Kreuscher S, Klepetko W, Grünig E.
Assessment of pulmonary artery systolic pressures by stress Doppler echocardiography after bilateral lung transplantation.
Journal of Heart and Lung Transplantation 2008;27:66-71.
PubMed


Möller T, Pettersen E, Peersen K, Fredriksen P, Holmstrøm H, Grünig E, Mereles D, Thaulow E.
Exercise-induced abnormal pulmonary arterial pressure response in adolescents and adults with atrial or ventricular septal defect.
Cardiology in the Young 2008;18:223.




2007

Buss S, Katus HA, Mereles D.
Dynamic changing mass behind the left atrium.
Heart 2007;93:1583.
PubMed


Buss SJ, Lehrke S, Katus HA, Mereles D.
Deep recessus of the muscular interventricular septum documented with echocardiography and magnetic resonance imaging.
International Journal of Cardiology 2007;120:e30-31.
PubMed


Reichenberger F, Koester M, Mereles D, Fijalkowska A, Weissmann S, Grunig E, Torbicki A, Olschewski H, Seeger W.
Cardiopulmonary exercise testing for detection of early pulmonary vascular changes in relatives of patients with idiopathic pulmonary arterial hypertension.
European Respiratory Journal 2007;30:S51,250s.


Scholz EP, Zitron E, Katus HA, Karle CA, Mereles D.
Atrial septal aneurysm mimicking ECG signs of enlarged right atrium.
Europace 2007;9:475-476.
PubMed


Mereles D, Ewert R, Lodziewski S, Borst MM, Benz A, Olschewski H, Grunig E.
Effect of Inhaled Iloprost during Off-Medication Time in Patients with Pulmonary Arterial Hypertension.
Respiration 2007;74:498-502.
PubMed


Dehnert C, Bartsch P, Grunig E, Mereles D.
High-altitude pulmonary edema and patent foramen ovale.
JAMA 2007;297:1432.
PubMed


Johanssen C, Mereles D, Hardt S, Buss SJ, Zeier M.
Liquefaction necrosis of mitral annulus calcification in a patient with chronic renal failure: an unrecognized diagnosis.
Clinical Nephrology 2007;67:126-128.
PubMed


Ley S, Mereles D, Puderbach M, Gruenig E, Schock H, Eichinger M, Ley-Zaporozhan J, Fink C, Kauczor HU.
Value of MR phase-contrast flow measurements for functional assessment of pulmonary arterial hypertension.
European Radiology 2007;17:1892-1897.
PubMed


Bär H, Mereles D, Libicher M, Katus HA.
Lariat-like sarcoma infiltration of the left atrium.
International Journal of Cardiology 2007;116:e51-52.
PubMed


Ley S, Mereles D, Risse F, Grunig E, Ley-Zaporozhan J, Tecer Z, Puderbach M, Fink C, Kauczor HU.
Quantitative 3D pulmonary MR-perfusion in patients with pulmonary arterial hypertension: Correlation with invasive pressure measurements.
European Journal of Radiology 2007;61:251-255.
PubMed




2006

Mereles D, Ehlken N, Kreuscher S, Ghofrani S, Hoeper MM, Halank M, Meyer FJ, Karger G, Buss J, Juenger J, Holzapfel N, Opitz C, Winkler J, Herth FF, Wilkens H, Katus HA, Olschewski H, Grunig E.
Exercise and Respiratory Training Improve Exercise Capacity and Quality of Life in Patients With Severe Chronic Pulmonary Hypertension.
Circulation 2006;114:1482-1489.
PubMed


Dehnert C, Risse F, Ley S, Kuder TA, Buhmann R, Puderbach M, Menold E, Mereles D, Kauczor HU, Bartsch P, Fink C.
Magnetic Resonance Imaging of Uneven Pulmonary Perfusion in Hypoxia in Humans.
American Journal of Respiratory and Critical Care Medicine 2006;174:1132-1138.
PubMed


Mereles D, Grunig E.
A Stepwise and Practical Approach to Optimizing Echocardiography in Pulmonary Hypertension.
Advances in Pulmonary Hypertension 2006;5:30-33. Erratum: Figure 3 has a subdivision, Figure 3a and 3b.
open source


Ehlken N, Mereles D, Ghofrani A, Hoeper M, Halank M, Meyer J, Karger G, Wilkens H, Herth F, Olschewski H, Grünig E.
Niedrig dosierte Atem- und Bewegungstherapie verbessert die körperliche Leistungsfähigkeit bei Patienten mit schwerer chronischer pulmonaler Hypertonie.
Pneumologie 2006;60:S19.


Mereles D, Ewert R, Lodziewski S, Borst M, Olschewski H, Grünig E.
Inhalative Therapie mit Iloprost verursacht nachts kein Rebound bei Patienten mit schwerer idiopathischer pulmonaler Hypertonie.
Pneumologie 2006;60:S27-S28.


Kasimir MT, Mereles D, Aigner C, Mazhar S, Jaksch P, Benz A, Kreuscher S, Klepetko W,Grünig E.
Systolischer pulmonalarterieller Druck während Belastung nach bilateraler Lungentransplantation.
Pneumologie 2006;60:S28.




2005

Grünig E, Dehnert C, Mereles D, Koehler R, Olschewski H, Bärtsch P, Janssen B.
Enhanced hypoxic pulmonary vasoconstriction in families of adults or children with idiopathic pulmonary arterial hypertension.
Chest 2005;128:630S-633S.
PubMed


Blessing E, Rottbauer W, Mereles D, Hosch W, Benz A, Friess H, Autschbach F, Muller M, Stremmel W, Katus H.
Isolated left ventricular noncompaction of the myocardium as a cause of embolic superior mesenteric artery occlusion.
Journal of the American Society of Echocardiography 2005;18:693-695.
PubMed


Dehnert C, Grünig E, Mereles D, von Lennep N, Bärtsch P.
Identification of individuals susceptible to high-altitude pulmonary oedema at low altitude.
European Respiratory Journal 2005;25:545-551.
PubMed




2004

Grünig E, Koehler R, Miltenberger-Miltenyi G, Zimmermann R, Gorenflo M, Mereles D, Arnold K, Naust B, Wilkens H, Benz A, Von Hippel A, Ulmer HE, Kübler W, Katus HA, Bartram CR, Schranz D, Janssen B.
Primary pulmonary hypertension in children may have a different genetic background than in adults.
Pediatric Research 2004;56:571-578.
PubMed




2003

Mereles D, Benz A, Kreuscher S, Aigner C, Mazhar S, Jaksch P, Kasimir M-T, Klepetko W, Katus HA, Grünig E.
Systolischer Pulmonalarteriendruck unter Belastung nach bilateraler Lungentransplantation.
Zeitschrift für Kardiologie 2003;92:105.


Benz A, Mereles D, Arnold K, Abushi A, Kücherer H, Katus HA, Grünig E.
Dopplersonographische Bestimmung des systolischen Pulmonalarteriendruckes unter Belastung: Was sind die Normgrenzen?
Zeitschrift für Kardiologie 2003;92:105-106.


Rindermann M, Grünig E, von Hippel A, Koehler R, Miltenberger-Miltenyi G, Mereles D, Arnold K, Pauciulo M, Nichols W, Olschewski H, Hoeper MM, Winkler J, Katus HA, Kübler A, Bartram CR, Janssen B.
Primary pulmonary hypertension may be a heterogeneous disease with a second locus on chromosome 2q31.
Journal of the American College of Cardiology 2003;41:2237-2244.
PubMed


Köhler R, Janssen B, von Hippel A, Mereles D, Benz A, Pauciulo M, Nichols W, Katus HA, Grünig E.
Häufigkeit der Mutationen des bone morphogenetic protein receptor 2 Gens bei Patienten mit primärer pulmonaler Hypertonie.
Zeitschrift für Kardiologie 2003;92:336.


Benz A, Mereles D, Katus HA, Kücherer H, Grünig E.
Longitudinale Familienuntersuchung bei familiärer dilatativer Kardiomyopathie.
Zeitschrift für Kardiologie 2003;92:337.


Grünig E, Benz A, Mereles D, Unnebrink K, Kucherer H, Haass M, Kubler W, Katus HA.
Prognostic value of serial cardiac assessment and familial screening in patients with dilated cardiomyopathy.
European Journal of Heart Failure 2003;5:55-62.
PubMed




2002

Mereles D, Arnold K, Olschewski H, Winkler J, Höper MM, Kübler W, Nichols W, Katus HA, Janssen B, Grünig E.
Frequency of familial primary pulmonary hypertension in a cohort study.
Circulation 2002;106:365.


Rindermann M, Janssen B, von Hippel A, Miltenberger-Miltenyi G, Mereles D, Olschewski H, Benz A, Katus HA, Grünig E.
Primary pulmonary hypertension: genetic heterogeneity and evidence for a second locus on 2q31-32.
Circulation 2002;106:365.


Grünig E, Mereles D, Benz A, Hansen A, Kübler W, Kuecherer H.
Contribution of stress echocardiography to clinical decision making in unselected ambulatory patients with known or suspected coronary artery disease.
International Journal of Cardiology 2002;84:179-185.
PubMed


Grünig E, Mereles D, Arnold K, Benz A, Olschewski H, Miltenberger-Miltenyi G, Borst MM, Abushi A, Seeger W, Winkler J, Höper MM, Bartram CR, Kübler W, Janssen B.
Primary pulmonary hypertension is predominantly a hereditary disease.
Chest 2002;121:81-82.
PubMed


Janssen B, Rindermann M, Barth U, Miltenberger-Miltenyi G, Mereles D, Abushi A, Seeger W, Kübler W, Bartram C, Grünig E.
Linkage analysis in a large family with primary pulmonary hypertension: genetic heterogeneity and a second primary pulmonary hypertension locus on 2q31-32.
Chest 2002;121:54-56.
PubMed


Arnold K, Dehnert C, Mereles D, Miltenberger-Miltenyi G, Rindermann M, Abushi A, Benz A, Kübler W, Bärtsch P, Janssen B, Grünig E.
Abnormale hypoxie Vasokonstriktion bei Genträgern der primären pulmonalen Hypertonie.
Zeitschrift für Kardiologie 2002;91:210.


Grünig E, Miltenberger-Miltenyi G, Mereles D, Arnold K, Benz A, Zimmermann R, Schranz D, Abushi A, Kübler K, Janssen B.
Primäre pulmonale Hypertonie bei Kinder.
Zeitschrift für Kardiologie 2002;91:176.




2001

Grünig E, Mereles D, Dehnert C, Arnold K, Miltenberger-Miltenyi G, Rindermann M, Abushi A, Kübler W, Janssen B, Bärtsch P.
Identification of susceptibility to primary pulmonary hypertension by Doppler-echocardiography during prolonged hypoxia.
Circulation 2001;104:502.


Baer H, Mereles D, Grünig E, Kuecherer H.
Exaggerated pectinate muscles mimicking multiple left atrial appendage thrombi.
European Journal of Echocardiography 2001;2:131.
PubMed


Hansen A, Mereles D, Kuecherer H.
Echocardiographic diagnosis of Bland-White-Garland syndrome.
Heart 2001;85:152.
PubMed




2000

Grünig E, Janssen B, Mereles D, Barth U, Borst MM, Vogt IR, Fischer C, Olschewski H, Kuecherer H, Kübler W.
Abnormal pulmonary artery response in asymptomatic carriers of primary pulmonary hypertension gene.
Circulation 2000;102:1145-1150.
PubMed


Grünig E, Mereles D, Hildebrandt W, Swenson E, Kübler W, Kücherer H, Bärtsch P.
Stress doppler echocardiography for identification of susceptibility for high altitude pulmonary edema.
Journal of the American College of Cardiology 2000;35:980-987.
PubMed


Viedt C, Mereles D, Kübler W, Kreuzer J.
Fibrinolytic therapy in thrombosis of a mitral valve prothesis.
Zeitschrift für Kardiologie 2000;89:698-701.
PubMed


Mereles D, Borst M, Barth U, Benz A, Kücherer H, Kübler W, Janssen B, Grünig E.
Identifikation von asymptomatischen Genträgern der familiären primären pulmonalen Hypertonie.
Zeitschrift für Kardiologie 2000;89:45.


Benz A, Mereles D, Borst M, Barth U, Abushi A, Kücherer H, Kübler W, Janssen B, Grünig E.
Prävalenz der familiären primären pulmonalen Hypertonie.
Zeitschrift für Kardiologie 2000;89:45.


Hansen A, Zugck C, Krüger C, Kell R, Unnebrink K, Mereles D, Kücherer H, Haass M.
Risikostratifizierung von Patienten mit chronischer Herzinsuffizienz anhand nichtinvasiver Parameter.
Zeitschrift für Kardiologie 2000;89:58.




1999

Hansen A, Zugck C, Krüger C, Kell R, Hardt S, Mereles D, Haass M, Kuecherer H.
Prognostic value of transmitral flow patterns in patients with chronic congestive heart failure.
European Heart Journal 1999;20:610.


Hansen A, Zugck C, Krueger C, Gerber S, Hardt S, Mereles D, Mura R, Haass M, Kuecherer H.
Prognostic value of Doppler echocardiographic transmitral flow patterns in 191 patients with congestive heart failure.
Journal of the American Society of Echocardiography 1999;12:395.


Grünig E, Ivandic B, Mereles D, Rottbauer W, Benz A, Janssen B, Kübler W.
Identifikation eines Genlokus auf Chromosom 1 in einer Familie mit autosomal verebter DCM und regionalen linksventrikulären Kontraktionsstörungen.
Zeitschrift für Kardiologie 1999;88:250.




1998

Grünig E, Mereles D, Hildebrandt W, Swenson E, Kuecherer H, Elser H, Busch T, Kübler W.
Stress-Echokardiographie zur Identifikation Höhenlungenödem anfälliger Personen.
Zeitschrift für Kardiologie 1998;87:293.


Grünig E, Wurster M, Mereles D, Barth-Witte U, Benz A, Kuecherer H, Katus H, Borst M, Janssen B.
Familiäre primäre pulmonale Hypertonie: Klinische Frühdiagnostik und Kopplungsanalyse in einer großen Familie.
Zeitschrift für Kardiologie 1998;87:240.


Gruenig E, Vogt I, Mereles D, Wurster M, Barth-Witte U, Kübler W, Kuecherer H, Borst M, Janssen B.
Familial primary pulmonary hypertension: early clinical diagnosis and linkage analysis in a large family.
Circulation 1998;98:673.




1997

Grünig E, Benz A, Meyer K, Mereles D, Kübler W, Kuecherer H, Katus HA.
Has the prognosis of dilated cardiomyopathy improved indeed?.
Journal of Heart Failure 1997;4:98.


Mereles D, Grünig E, Katus H, Kübler W, Kuecherer H.
Impact of stress echocardiography on clinical decision making in ambulatory patients with known or suspected coronary artery disease.
European Heart Journal 1997;18:554.


Gruenig E, Mereles D, Hildebrandt W, Swenson E, Kuecherer H, Busch T, Bärtsch P.
Hypertensive pulmonary response to exercise and to hypoxia in subjects with prior high altitude pulmonary edema measured by stress echocardiography.
Circulation 1997;96:427.


Mereles D, Gruenig E, Kuecherer H.
What is the impact of stress echocardiography on clinical decision making?
Circulation 1997;96:387.


Glombitza G, Makabe M, Hardt S, Mereles D, Meinzer H, Kuecherer H, Kübler W.
3-dimensionale Echokardiographie: Vergleich volumetrischer Methoden für rotationsakquirierte Bilddaten.
Zeitschrift für Kardiologie 1997;39:133.


Kuecherer H, Glombitza G, Makabe M, Hardt S, Mereles D, Meinzer H, Kübler W.
3-dimensionale Echokardiographie: In-vitro-Studie zur Anwendung eines neuen volumenorientierten Rekonstruktionsverfahren.
Zeitschrift für Kardiologie 1997;39:147.




1996 - 1989

Frank S, Mereles D, Kücherer H, Kübler W.
Beziehung zwischen Pulmonalvenenfluß und Lebensalter.
Zeitschrift für Kardiologie 1996;85:31.


Mereles D, Hardt S, Kücherer H.
Contrast in echocardiography: diagnostic value in transthoracic and transesophageal examinations.
VI Paraguayan Congress of Cardiology, Asunción, September 1995.


Mereles D.
Clinical value of the interrogation or the pulmonary vein flow during transesophageal echocardiography.
Scientific Session of the Paraguayan Society of Cardiology, October 1994.


Mereles D, Barrios L, Diaz Jure R, Sosa O.
Intravenous diltiazem for acute atrial fibrillation.
Scientific Session of the Paraguayan Society of Cardiology, September 1993.
Published in Anales de la Facultat de Ciencias Médicas, Asunción, Paraguay 1993.


Mereles D, Barrios L.
Dobutamin-Stress-Echocardiography: first experiences in Paraguay.
Scientific Session of the Paraguayan Society of Cardiology, May 1992.


Mereles D, Barrios L, Sosa O.
Intracavitary thombus in dilated cardiomyopathy.
First Paraguayan Congress of Internal Medicine, April 1990.
Scientific Session of the Paraguayan Society of Cardiology, July 1990.


Mereles D, Barrios L, Sosa O.
Familial cardiomyopathy.
Scientific Session of the Paraguayan Society of Cardiology, August 1989.



[arriba]